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  • Institution/s: Rheinische Friedrich-Wilhelms-Universität Bonn, Universidad de Alicante, Universidad de Valladolid, Université d'Artois
  • Project: Diccionario Terminológico de Genética (Eurogene)
  • Identification number: 157
  • Subdomains: Studies of chromatin, Studies of DNA, Studies of RNA, Techniques
  • Author/s: Beatriz BURGOS CUADRILLERO, Marie-Hélène GARCIA, Marina BOX ALBERO, Teresa AMIDO LOZANO
  • Creation / modification date: 27-02-2014
  • Term: mitochondria
  • Gramatical category: s
  • Definition: Mitochondria are tiny structures found in cells (one is called a mitochondrion). Respiration, the chemical reaction that releases energy from glucose, happens in mitochondria. This provides energy for life process such as movement and growth. Tissues and organs that need a lot of energy have large numbers of mitochondria in their cells. For example, liver cells and muscle cells contain a lot of mitochondria.
  • Context: There are many methods to measure mitochondrial function and dysfunction in these systems. Generally, measurements of fluxes give more information about the ability to make ATP than do measurements of intermediates and potentials. For isolated mitochondria, the best assay is mitochondrial respiratory control: the increase in respiration rate in response to ADP.
  • Expression: Assessing mitochondrial dysfunction in cells
  • Weighting mark: nor
  • Sources:
    • Term: EMERY, A.E.H. y MUELLER, R.F. (1992) Elements of Medical Genetics, Churchill Livingstone: New York. 8th Edition.
    • Definition: BBC -Bitesize (2013) „Molecules of life“. Recuperado el 23 de diciembre de 2013 de: http://www.bbc.co.uk/schools/gcsebitesize/science/add_ocr_gateway/living_growing/moleculesrev1.shtml
    • Context: BRAND, M. Y NICHOLLS, D. (2011) „Assessing mitochondrial dysfunction in cells“. Biochem J, 2011. 435(Pt 2): 297-312. Recuperado el 23 de diciembre de 2013 de:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076726/
    • Expression: BRAND, M. Y NICHOLLS, D. (2011) „Assessing mitochondrial dysfunction in cells“. Biochem J, 2011. 435(Pt 2): 297-312. Recuperado el 23 de diciembre de 2013 de:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076726/
  • Images:
    • mitocondria
      http://www.chemgapedia.de/vsengine/vlu/vsc/de/ch/8/bc/vlu/transport/proteintransport2.vlu/Page/vsc/de/ch/8/bc/transport/protein_euk_mito.vscml.html (abgerufen im November 2013).
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