- Institution/s: Rheinische Friedrich-Wilhelms-Universität Bonn, Universidad de Alicante, Universidad de Valladolid
- Project: Diccionario Terminológico de Genética (Eurogene)
- Identification number: 172
- Subdomains: Studies of chromatin, Studies of DNA, Studies of RNA, Techniques
- Author/s: Augustine Edith EMENE, Beatriz BURGOS CUADRILLERO, Héctor BOLORINOS RUIZ, Verónica ARNÁIZ UZQUIZA
- Creation / modification date: 01-02-2014
- Term: abnormality –ies (See chromosomal abnormality)
- Gramatical category: s
- Definition: Rearrangement (deletion, duplication, inversion or translocation), or presence of an altered number of chromosomes (aneuploidy and polyploidy).
- Context: The first evidence in vivo came from the analysis of replication timing of human chromosome 22 carrying a chromosomal abnormality frequently observed in pathologies such as cancer or genetic diseases.
- Expression: Chromosomal abnormality , chromosome abnormality
- Notes: Frequently replaced by the form “Chromosomal abnormality” in specialized contexts”. In lesser specialized texts the form “abnormality” has a general meaning (altered situation).
- Weighting mark: nor
- Sources:
- Term: RINGO, J. (2004), Fundamental Genetics, Cambridge: Cambridge University Press. 191
- Definition: RINGO, J. (2004), Fundamental Genetics, Cambridge: Cambridge University Press. 191
- Context: TOLLEFSBOL, T. (2011) Handbook in Epigenetics: The New Molecular and Medical Genetics, London: Elsevier. 81
- Expression: TOLLEFSBOL, T. (2011) Handbook in Epigenetics: The New Molecular and Medical Genetics, London: Elsevier. 81; LEWIS, R. (2010) Human Genetics: The Basics, New York: Routledge. 44.
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