edugeneedugene2013
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  • Institution/s: Universidad de Valladolid
  • Project: Diccionario Terminológico de Genética (Eurogene)
  • Identification number: 101
  • Subdomains: Studies of chromatin, Studies of DNA, Studies of RNA, Techniques
  • Author/s: Ana MUÑOZ GASCÓN, Augustine Edith EMENE, Susana ALVAREZ ALVAREZ
  • Creation / modification date: 04-02-2014
  • Term: DNA polymerase
  • Gramatical category: s
  • Definition: An enzyme that catalyzes (speeds) the polymerization of DNA. DNA polymerase uses preexisting nucleic acid templates and assembles the DNA from deoxyribonucleotides; it is necessary for the incorporation of precursor substances into new DNA.
  • Context: In the yeast Saccharomyces cerevisiae, reduced levels of the replicative α DNA polymerase result in greatly elevated frequencies of chromosome translocations and chromosome loss. We selected translocations in a small region of chromosome III and found that they involve homologous recombination events between yeast retrotransposons (Ty elements) on chromosome III and retrotransposons located on other chromosomes.
  • Weighting mark: nor
  • Sources:
    • Term: EMERY, A. (2009), Elementos de genética médica. Barcelona: Ed. Elsevier, 13ª Edición (revisión científica a cargo del Dr. Rafael Oliva Virgili).
    • Definition: http://medmol.es/glosario/65/
    • Context: PICHER SERANTES, A.J. (2007) Papel de la ADN polimerasa λ humana en reparación de daño oxidativo y roturas de doble cadena en el ADN. Tesis Doctoral. Universidad Autónoma de Madrid. Disponible en línea. http://digital.csic.es/handle/10261/8047
  • Images:
    • DNA polymerase
      http://es.wikipedia.org/wiki/ADN_polimerasa
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