edugeneedugene2013
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  • Institution/s: Universidad de Alicante, Universidad de Valladolid
  • Project: Diccionario Terminológico de Genética (Eurogene)
  • Identification number: 185
  • Subdomains: Studies of chromatin, Studies of DNA, Studies of RNA, Techniques
  • Author/s: Augustine Edith EMENE, Carmen CUÉLLAR LÁZARO, Isaac MORENO RUIZ, Pablo Eduardo VALLINAS GARCÍA, Susana ALVAREZ ALVAREZ
  • Creation / modification date: 27-02-2014
  • Term: nucleosome
  • Gramatical category: s
  • Definition: Any of the repeating subunits of chromatin, consisting of a DNA chain coiled around a core of histones.
  • Context: The nanobioconjugate carries anti-tumor nucleosome monoclonal antibody (mAb) 2C5 to target breast cancer cells, anti-mouse transferrin receptor (TfR) antibody for drug delivery through the host endothelial system, and Morpholino antisense oligonucleotide (AON) to inhibit EGFR synthesis.
  • Weighting mark: nor
  • Sources:
    • Term: EMERY, A. (2009), Elementos de genética médica. Barcelona: Ed. Elsevier, 13ª Edición. (Revisión científica a cargo del Dr. Rafael Oliva Virgili).
    • Definition: MARTÍNEZ, V. (2013). “Nucleosoma”, Biotech Spain. Recuperado el 15 de noviembre de 2013 de: http://biotechspain.com/es/molecula.cfm?iid=nucleosome
    • Context: MARTÍNEZ, V. (2013). “Nucleosoma”, Biotech Spain. Recuperado el 15 de Noviembre de 2013 de: http://biotechspain.com/es/molecula.cfm?iid=nucleosome
  • Images:
    • nuclosome
      http://commons.wikimedia.org/wiki/File:Nukleosom.png (abgerufen im August 2013).
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