edugeneedugene2013
All
  • Institution/s: Universidad de Valladolid
  • Project: Diccionario Terminológico de Genética (Eurogene)
  • Identification number: 21
  • Subdomains: Studies of chromatin, Studies of DNA, Studies of RNA, Techniques
  • Author/s: Marta VALDENEBRO ARENAS, Patricia ROJO DE DOMINGO, Regina CAVA GARCÍA, Rubén ORTIZ PAMPLIN
  • Creation / modification date: 01-03-2014
  • Term: proto-oncogene(s)
  • Gramatical category: s
  • Definition: A gene having the potential for change into an active oncogene.
  • Context: We hypothesized that 3'UTR SNPs in miRNA binding sites of proto-oncogenes could abrogate their post-transcriptional regulation, resulting in overexpression of oncogenic proteins, tumor initiation, progression, and modulation of drug response in cancer patients.
  • Expression: Proto-oncogene is activated Activated proto-oncogene
  • Weighting mark: nor
  • Sources:
    • Term: SCHAAF, Christian, ZSCHOCKE, Johannes (2013). Basiswissen Humangenetik. 2. Aufl. Berlin, Heidelberg: Springer Verlag, 85.
    • Definition: SCHAAF, Christian, ZSCHOCKE, Johannes (2013). Basiswissen Humangenetik. 2. Aufl. Berlin, Heidelberg: Springer Verlag, 85.
    • Context: MURKEN, Jan (Hrsg.) (2011). Humangenetik. 8. Aufl. Stuttgart: Thieme, 518.
  • Images:
    • proto-oncogene(s)
      http://bio1151.nicerweb.com/Locked/media/ch18/proto-oncogene.html
See this term in