- Institution/s: Universidad de Valladolid
- Project: Diccionario Terminológico de Genética (Eurogene)
- Identification number: 84
- Subdomains: Studies of chromatin, Studies of DNA, Studies of RNA, Techniques
- Author/s: Ana MUÑOZ GASCÓN, Ana María MALLO LAPUERTA, Cristina ADRADA RAFAEL, Teresa AMIDO LOZANO
- Creation / modification date: 01-03-2014
- Term: endoplasmic reticulum
- Gramatical category: s
- Definition: The endoplasmic reticulum is a network of flattened sacs and branching tubules that extends throughout the cytoplasm in plant and animal cells. It is a multifold membranous strucutre within eukaryotic cells which plays a major role inn the synthesis of the comples molecules required by the cell and the organism as a whole.
- Context: Up-regulation of class I MHC in skeletal muscle fibers was an early and consistent feature of human inflammatory myopathies. [...]The pathways of endoplasmic reticulum (ER) stress response, [...] and the ER overload response (NF-kappaB pathway) were significantly activated in muscle tissue of human myositis patients [...] not degradable glycosylation mutants of H-2K(b) induced ER stress response in C(2)C(12) skeletal muscle cells.
- Expression: Endoplasmic reticulum membrane.
- Notes: The sacs and tubules of the endoplasmic reticulum are all interconnected by a single continuous membrane so that the organelle has only one large, highly convoluted and complexly arranged lumen. The endoplasmic reticulum membrane allows molecules to be s
- Weighting mark: nor
- Sources:
- Term: PASSARGE, Eberhard (2008). Taschenatlas Humangenetik. Stuttgart: Georg Thieme Verlag, 371.
- Definition: PASSARGE, Eberhard (2008). Taschenatlas Humangenetik. Stuttgart: Georg Thieme Verlag, 371.
- Context: SEYFFERT, Willhelm (2003). Lehrbuch der Genetik. Heidelberg: Spektrum Akademischer Verlag, 960.
- Images:
www.ulysse.u-bordeaux.fr
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