- Institution/s: Universidad de Alicante, Universidad de Valladolid
- Project: Diccionario Terminológico de Genética (Eurogene)
- Identification number: 185
- Subdomains: Studies of chromatin, Studies of DNA, Studies of RNA, Techniques
- Author/s: Augustine Edith EMENE, Carmen CUÉLLAR LÁZARO, Isaac MORENO RUIZ, Pablo Eduardo VALLINAS GARCÍA, Susana ALVAREZ ALVAREZ
- Creation / modification date: 27-02-2014
- Term: nucleosome
- Gramatical category: s
- Definition: Any of the repeating subunits of chromatin, consisting of a DNA chain coiled around a core of histones.
- Context: The nanobioconjugate carries anti-tumor nucleosome monoclonal antibody (mAb) 2C5 to target breast cancer cells, anti-mouse transferrin receptor (TfR) antibody for drug delivery through the host endothelial system, and Morpholino antisense oligonucleotide (AON) to inhibit EGFR synthesis.
- Weighting mark: nor
- Sources:
- Term: JANNING, Wilfried, KNUST, Elisabeth (2008). Genetik. Allgemeine Genetik - Molekulare Genetik - Entwicklungsgenetik. Stuttgart: Georg Thieme Verlag, 494. SEYFFERT, Wilhelm (Hrsg.) (2003). Lehrbuch der Genetik. Berlin: Spektrum Akademischer Verlag, 226
- Definition: SEYFFERT, Wilhelm (Hrsg.) (2003). Lehrbuch der Genetik. Berlin: Spektrum Akademischer Verlag, 226
- Context: PASSARGE, Eberhard (2008). Taschenatlas. Humangenetik. 3. Aufl. Stuttgart: Georg Thieme Verlag, 120.
- Images:
http://commons.wikimedia.org/wiki/File:Nukleosom.png (abgerufen im August 2013).
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