Definition: Indicator that signals there have been deletions at both ends of a chromosome and that the deleted ends, which are more ‘sticky’, have adhered to each other to form a ring.
Context: In patients with ring chromosomes, sister chromatid exchanges occurring during mitosis usually result in secondary chromosomal abnormalities, such as dicentric rings, interlocked rings, and other structural conformations.
Weighting mark: nor
Sources:
Term: KEPES, François (2005). « L’épigénétique comme aspect de la postgénomique ». In Erudit. M/S : médecine science, 21, 4, 371-376.