Definition: Indicator that signals there have been deletions at both ends of a chromosome and that the deleted ends, which are more ‘sticky’, have adhered to each other to form a ring.
Context: In patients with ring chromosomes, sister chromatid exchanges occurring during mitosis usually result in secondary chromosomal abnormalities, such as dicentric rings, interlocked rings, and other structural conformations.
Weighting mark: nor
Sources:
Term: EMERY, A. (2009), Elementos de genética médica. Barcelona: Ed. Elsevier, 13ª Edición. (Revisión científica a cargo del Dr. Rafael Oliva Virgili).
Definition: Hospital Universitario Nuestra Señora de Valme (Sevilla). Cromosoma 21 en anillo. Recuperado el 23 de noviembre de 2013 http://www.spao.es/documentos/boletines/pdf-boletin-seccion-15-secciones-34358.pdf
Context: Instituto Químico Biológico. Cromosomas y enfermedades. Recuperado el 21 de noviembre de 2013, http://www.iqb.es/cromosomas/anomalias.htm
Images:
US National Library of Medicine, Genetics Home Reference: Your Guide to Understanding Genetic Conditions: