- Institution/s: Universidad de Alicante, Universidad de Valladolid
- Project: Diccionario Terminológico de Genética (Eurogene)
- Identification number: 187
- Subdomains: Studies of chromatin, Studies of DNA, Studies of RNA, Techniques
- Author/s: Andrea COCCARO CASTILLO, Augustine Edith EMENE, Carmen CUÉLLAR LÁZARO, Isaac MORENO RUIZ
- Creation / modification date: 01-02-2014
- Term: nucleic acid
- Gramatical category: s
- Definition: Any of a group of complex compounds found in all living cells and viruses, composed of purines, pyrimidines, carbohydrates, and phosphoric acid. Nucleic acids in the form of DNA and RNA control cellular function and heredity.
- Context: Introduction of use of nanoparticle based systems could improve the drug uptake and cytotoxity due to the coexistence of the chemosensitizer, anticancer drugs, and perhaps short nucleic acids such as MDR1siRNA in the same cell, but the precise mechanism of interaction warrants further investigation.
- Weighting mark: nor
- Sources:
- Term: EMERY, A.E.H. y MUELLER, R.F. (1992) Elements of Medical Genetics, Churchill Livingstone: New York. 8th Edition.
- Definition: The American Heritage Science Dictionary. (2005). Consultado el 28 de enero de 2014
- Context: SUSA, M. et al (2009) .Doxorubicin loaded polymeric nanoparticulate delivery system to overcome drug resistance in osteosarcoma. Bouvé Faculty Publications. Paper 2. http://hdl.handle.net/2047/d20000293 (Consultado el 28 de enero de 2014).
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