- Institution/s: Universidad de Valladolid, Universitatea de Vest din Timişoara
- Project: Diccionario Terminológico de Genética (Eurogene)
- Identification number: 144
- Subdomains: Studies of chromatin, Studies of DNA, Studies of RNA, Techniques
- Author/s: Bianca CONSTANTINESCU, Isaac MORENO RUIZ, María Eugenia HERRERAS , Marta VALDENEBRO ARENAS
- Creation / modification date: 01-02-2014
- Term: gene repression
- Gramatical category: s
- Definition: The inhibition of gene transcription of an operon; in prokaryotes the mechanism involves binding of the operon by a repressor, sometimes also requiring the binding of a corepressor or absence of an inducer. The end result is frequently a decrease in the level of an enzyme.
- Context: The chosen strategy for finding tissue-specific gene repression was also applied to the liver as baseline instead of islets (5), and this resulted in the identification of liver-specifically repressed genes as the mirror situation of liver-specific genes.
- Weighting mark: nor
- Remission: abrform, SRY. Source: EMERY, A.E.H. y MUELLER, R.F. (1992) Elements of Medical Genetics, Churchill Livingstone: New York. 8th Edition (p. 95).
- Sources:
- Term: EMERY, A. (2009), Elementos de genética médica. Barcelona: Ed. Elsevier, 13ª Edición (revisión científica a cargo del Dr. Rafael Oliva Virgili).
- Definition: Diccionario Español Collins – Octava edición. (2005). William Collins Sons et al. HarperCollins Publishers 2005. Consultado el 25 de enero de 2014.
- Context: Dorland B. Diccionario enciclopédico ilustrado de medicina (2 vols.). Madrid: McGraw-Hill; 1992.
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