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  • Institution/s: Universidad de Valladolid
  • Project: Diccionario Terminológico de Genética (Eurogene)
  • Identification number: 84
  • Subdomains: Studies of chromatin, Studies of DNA, Studies of RNA, Techniques
  • Author/s: Ana MUÑOZ GASCÓN, Ana María MALLO LAPUERTA, Cristina ADRADA RAFAEL, Teresa AMIDO LOZANO
  • Creation / modification date: 01-03-2014
  • Term: endoplasmic reticulum
  • Gramatical category: s
  • Definition: The endoplasmic reticulum is a network of flattened sacs and branching tubules that extends throughout the cytoplasm in plant and animal cells. It is a multifold membranous strucutre within eukaryotic cells which plays a major role inn the synthesis of the comples molecules required by the cell and the organism as a whole.
  • Context: Up-regulation of class I MHC in skeletal muscle fibers was an early and consistent feature of human inflammatory myopathies. [...]The pathways of endoplasmic reticulum (ER) stress response, [...] and the ER overload response (NF-kappaB pathway) were significantly activated in muscle tissue of human myositis patients [...] not degradable glycosylation mutants of H-2K(b) induced ER stress response in C(2)C(12) skeletal muscle cells.
  • Expression: Endoplasmic reticulum membrane.
  • Notes: The sacs and tubules of the endoplasmic reticulum are all interconnected by a single continuous membrane so that the organelle has only one large, highly convoluted and complexly arranged lumen. The endoplasmic reticulum membrane allows molecules to be s
  • Weighting mark: nor
  • Sources:
    • Term: EMERY, A.E.H. y MUELLER, R.F. (1992) Elements of Medical Genetics, Churchill Livingstone: New York. 8th Edition.
    • Definition: W. DAVIDSON, Michael, The Florida State University (2004). „The Endoplasmic Reticulum“. Recuperado el 24 de abril de 2013 de: http://micro.magnet.fsu.edu/cells/endoplasmicreticulum/endoplasmicreticulum.html
    • Context: NAGARAJAU, K. et ali (2005). „Activation of the endoplasmic reticulum stress response in autoimmune myositis: potential role in muscle fiber damage and dysfunction“. Recuperado el 21 de abril de 2013 de: http://www.ncbi.nlm.nih.gov/pubmed/15934115
    • Expression: W. DAVIDSON, Michael, The Florida State University (2004). „The Endoplasmic Reticulum“. Recuperado el 24 de abril de 2013 de: http://micro.magnet.fsu.edu/cells/endoplasmicreticulum/endoplasmicreticulum.html
    • Notes: W. DAVIDSON, Michael, The Florida State University (2004). „The Endoplasmic Reticulum“. Recuperado el 24 de abril de 2013 de: http://micro.magnet.fsu.edu/cells/endoplasmicreticulum/endoplasmicreticulum.html NAVE, R. (2001). „Endoplasmic Reticulum.“ Hyperphysics, Georgia State University. Recuperado el 29 de abril de 2013 de: http://hyperphysics.phy-astr.gsu.edu/hbase/biology/endret.html
  • Images:
    • endoplasmic reticulum
      www.ulysse.u-bordeaux.fr
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