- Institution/s: Universidad de Valladolid
- Project: Diccionario Terminológico de Genética (Eurogene)
- Identification number: 21
- Subdomains: Studies of chromatin, Studies of DNA, Studies of RNA, Techniques
- Author/s: Marta VALDENEBRO ARENAS, Patricia ROJO DE DOMINGO, Regina CAVA GARCÍA, Rubén ORTIZ PAMPLIN
- Creation / modification date: 01-03-2014
- Term: proto-oncogene(s)
- Gramatical category: s
- Definition: A gene having the potential for change into an active oncogene.
- Context: We hypothesized that 3'UTR SNPs in miRNA binding sites of proto-oncogenes could abrogate their post-transcriptional regulation, resulting in overexpression of oncogenic proteins, tumor initiation, progression, and modulation of drug response in cancer patients.
- Expression: Proto-oncogene is activated Activated proto-oncogene
- Weighting mark: nor
- Sources:
- Term: EMERY, A.E.H. y MUELLER, R.F. (1992) Elements of Medical Genetics, Churchill Livingstone: New York. 8th Edition.
- Definition: U.S. Department of Health and Human Services. MedlinePlus medical dictionary. National Institutes of Health. [En línea]. Recuperado el 1 de diciembre de 2013 en: http://www.merriam-webster.com/medlineplus/Proto-oncogene
- Context: MANIKANDAN, M. A. (2013). Single Nucleotide Polymorphisms in MicroRNA Binding Sites of Oncogenes: Implications in Cancer and Pharmacogenomics. Chennai.: Department of Genetics, Dr. ALM PG Institute of Basic Medical Sciences, University of Madras , Taram
- Expression: British National Corpus. Nature. London: Macmillan Magazines Ltd, 1993. University of Oxford [En Línea]. Recuperado el 1 de diciembre de 2013 en: http://bnc.bl.uk/saraWeb.php?qy=oncogene&mysubmit=Go
- Images:
http://bio1151.nicerweb.com/Locked/media/ch18/proto-oncogene.html
See this term in
