edugeneedugene2013
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  • Institution/s: Universidad de Alicante, Universidad de Valladolid
  • Project: Diccionario Terminológico de Genética (Eurogene)
  • Identification number: 185
  • Subdomains: Studies of chromatin, Studies of DNA, Studies of RNA, Techniques
  • Author/s: Augustine Edith EMENE, Carmen CUÉLLAR LÁZARO, Isaac MORENO RUIZ, Pablo Eduardo VALLINAS GARCÍA, Susana ALVAREZ ALVAREZ
  • Creation / modification date: 27-02-2014
  • Term: nucleosome
  • Gramatical category: s
  • Definition: Any of the repeating subunits of chromatin, consisting of a DNA chain coiled around a core of histones.
  • Context: The nanobioconjugate carries anti-tumor nucleosome monoclonal antibody (mAb) 2C5 to target breast cancer cells, anti-mouse transferrin receptor (TfR) antibody for drug delivery through the host endothelial system, and Morpholino antisense oligonucleotide (AON) to inhibit EGFR synthesis.
  • Weighting mark: nor
  • Sources:
    • Term: EMERY, A.E.H. y MUELLER, R.F. (1992) Elements of Medical Genetics, Churchill Livingstone: New York. 8th Edition.
    • Definition: The American Heritage Science Dictionary. (2005). Consultado el 28 de enero de 2014
    • Context: INOUE, S. et al. (2012)
  • Images:
    • nuclosome
      http://commons.wikimedia.org/wiki/File:Nukleosom.png (abgerufen im August 2013).
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