- Institution/s: Universidad de Alicante, Universidad de Saarbrücken, Universidad de Valladolid, Universitatea de Vest din Timişoara
- Project: Diccionario Terminológico de Genética (Eurogene)
- Identification number: 74
- Subdomains: Studies of chromatin, Studies of DNA, Studies of RNA, Techniques
- Author/s: Andrea COCCARO CASTILLO, Bianca CONSTANTINESCU, Gloria GONZÁLEZ-CALERO, María Eugenia HERRERAS
- Creation / modification date: 30-01-2014
- Term: chromatid
- Gramatical category: s
- Definition: One of two identical halves of a replicated chromosome. During cell division, the chromosomes first replicate so that each daughter cell receives a complete set of chromosomes. Following DNA replication, the chromosome consists of two identical structures called sister chromatids, which are joined at the centromere.
- Context: The spindle checkpoint detects improper kinetochore-microtubule attachments and translates these defects into biochemical activities that inhibit the anaphase-promoting complex or cyclosome (APC/C) throughout the cell to delay anaphase onset. A deficient spindle checkpoint leads to premature sister-chromatid separation and aneuploidy.
- Weighting mark: nor
- Remission: sin, anomalie génétique . Source: http://www.ac-nancy-metz.fr/enseign/svt/eleve/cyber/Vincent/anogenes.htm .
- Sources:
- Term: EMERY, A. (2009), Elementos de genética médica. Barcelona: Ed. Elsevier, 13ª Edición. (Revisión científica a cargo del Dr. Rafael Oliva Virgili).
- Definition: http://ocw.um.es/gat/contenidos/mjmarti/BiopatologiaDiscapacidadWiky/Glosario%20Biopatologia.pdf
- Context: RODRIGO GUTIÉRREZ, J.C (2010) Estudio de los reguladores del ciclo celular asociados al desarrollo de cáncer oral en una muestra de la provincia de Álava. Madrid: Universidad Complutense de Madrid.
- Notes: Real Academia Nacional de Medicina (2012). Diccionario de términos médicos. Madrid: Editorial Médica Panamericana.
- Images:
http://svt-barcelo.fr/3emes/aide/chromosomes_chromatides.php
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