edugeneedugene2013
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  • Institution/s: Rheinische Friedrich-Wilhelms-Universität Bonn, Universidad de Alicante, Universidad de Valladolid, Université d'Artois
  • Project: Diccionario Terminológico de Genética (Eurogene)
  • Identification number: 154
  • Subdomains: Studies of chromatin, Studies of DNA, Studies of RNA, Techniques
  • Author/s: Beatriz BURGOS CUADRILLERO, Eva HERNÁNDEZ SORIANO, Marie-Hélène GARCIA, Teresa AMIDO LOZANO
  • Creation / modification date: 27-02-2014
  • Term: messenger-RNA
  • Gramatical category: s
  • Definition: Messenger RNA (mRNA) is a single-stranded RNA molecule that is complementary to one of the DNA strands of a gene. The mRNA is an RNA version of the gene that leaves the cell nucleus and moves to the cytoplasm where proteins are made. During protein synthesis, an organelle called a ribosome moves along the mRNA, reads its base sequence, and uses the genetic code to translate each three-base triplet, or codon, into its corresponding amino acid.
  • Context: Stem cells can differentiate into all the specialized tissues and can replenish the specialized cells that have been lost because of injury, disease, or aging. Now, scientists from three schools of the University of Pennsylvania have found another way to change one cell type into another – by using messenger RNAs.
  • Expression: Messenger RNAs are associated with RNA-binding proteins
  • Weighting mark: nor
  • Sources:
    • Term: EMERY, A.E.H. y MUELLER, R.F. (1992) Elements of Medical Genetics, Churchill Livingstone: New York. 8th Edition.
    • Definition: National Human Genome Research Institute. „Messenger-RNA“. Recuperado el 23 de diciembre de 2013 de: http://www.genome.gov/glossary/?id=123
    • Context: KREEGER, Karen (2008) „RNA: Cell Reprogrammer“. Recuperado el 23 de diciembre de 2013 de: http://www.uphs.upenn.edu/news/publications/PENNMedicine/files/PENNMedicine_2009_02_spring30_rna-cell-reprogramming.pdf
    • Expression: DREYFUSS, G. Et ali (2002) „Messenger-RNA-Binding proteins and the messages they carry“. Nature Reviews, Molecular Cell Biology. Recuperado el 23 de diciembre de 2013 de: http://pt7mdv.ceingebi.unam.mx/computo/pdfs/cursosviejos/bcelularII02/bcelular/D
  • Images:
    • messenger-RNA
      http://www2.uni-jena.de/ufk/cdVorlesung/ovar.htm (abgerufen im November 2013).
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