Institution/s: Universidad de Valladolid, Universitatea de Vest din Timişoara
Project: Diccionario Terminológico de Genética (Eurogene)
Identification number: 143
Subdomains: Studies of chromatin, Studies of DNA, Studies of RNA, Techniques
Author/s: Bianca CONSTANTINESCU, Isaac MORENO RUIZ, María Eugenia HERRERAS , Marta VALDENEBRO ARENAS
Creation / modification date: 01-02-2014
Term: DNA replication
Gramatical category: s
Definition: A complex process whereby the 'parent' strands of DNA in the double helix are separated, and each one is copied to produce a new (daughter) strand. This process is said to be 'semiconservative' because one strand from each parent is conserved and remains intact after replication has taken place.
Context: Five distinct patterns of DNA replication have been identified during S-phase in asynchronous and synchronous cultures of mammalian cells by conventional fluorescence microscopy, confocal laser scanning microscopy, and immunoelectron microscopy.
Weighting mark: nor
Sources:
Term: EMERY, A.E.H. y MUELLER, R.F. (1992) Elements of Medical Genetics, Churchill Livingstone: New York. 8th Edition.
Context: RAYMOND T. ET AL. Dynamic Organization of DNA Replication in Mammalian Cell Nuclei: Spatially and Temporally Defined Replication of Chromosome-specific a-Satellite DNA Sequences. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724-2217; And Graduate Program In Molecular And Cellular Biology, State University Of New York At Stony Brook, Stony Brook, New York 11794-5200 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2289349/pdf/jc11651095.pdf