Institution/s: Universidad de Alicante, Universidad de Valladolid
Project: Diccionario Terminológico de Genética (Eurogene)
Identification number: 169
Subdomains: Studies of chromatin, Studies of DNA, Studies of RNA, Techniques
Author/s: Augustine Edith EMENE, Marta VALDENEBRO ARENAS, Rosa María FERRERAS LOZANO, Victoria PASTOR DE MEER
Creation / modification date: 01-02-2014
Term: consanguineous marriage
Gramatical category: s
Definition: A union between two individuals who are related as second cousins or closer, with the inbreeding coefficient (F) equal or higher than 0.0156, where (F) represents a measure of the proportion of loci at which the offspring of a consanguineous union is expected to inherit identical gene copies from both parents.
Context: The high consanguinity rates, coupled by the large family size in some communities, could induce the expression of autosomal recessive diseases, including very rare or new syndromes which increase the public awareness of the risks associated with consanguineous marriages.
Weighting mark: nor
Sources:
Term: EMERY, A.E.H. y MUELLER, R.F. (1992) Elements of Medical Genetics, Churchill Livingstone: New York. 8th Edition.
Definition: HAMAMY, H. (2012) Consanguineous marriages: Preconception consultation in primary health care settings. Journal of Community Genetics. Vol. 3. pp. 185-192 [Online] Available at: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419292/ [Accessed 29 April 2013]
Context: HAMAMY, H. (2012) Consanguineous marriages: Preconception consultation in primary health care settings. Journal of Community Genetics. Vol. 3. pp. 185-192 [Online] Available at: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419292/ [Accessed 29 April 2013]