- Institution/s: Universidad de Alicante, Universidad de Valladolid, Universitatea de Vest din Timişoara
- Project: Diccionario Terminológico de Genética (Eurogene)
- Identification number: 104
- Subdomains: Studies of chromatin, Studies of DNA, Studies of RNA, Techniques
- Author/s: Diana MOŢOC, Elena SERRANO BERTOS, Marta VALDENEBRO ARENAS, Verónica ARNÁIZ UZQUIZA
- Creation / modification date: 04-02-2014
- Term: restriction fragment length polymorphisms
- Gramatical category: s
- Definition: Difference in homologous DNA sequences that can be detected by the presence of fragments of different lengths after digestion of the DNA samples in question with specific restriction endonucleases.
- Context: Developments in recombinant DNA technology utilizing the phenomenon of restriction fragment length polymorphisms mean that the number of single-gene disorders in which this is possible is rapidly increasing.
- Expression: Terminal restriction fragment length polymorphism (T-RFLP), RFLP probe, RFLP method
- Notes: Often pronounced “rif lip”, as if it were a word. English abbreviated form used in other languages (Spanish)
- Weighting mark: nor
- Sources:
- Term: MURKEN, Jan (Hrsg.) (2011). Humangenetik. 8. Aufl. Stuttgart: Thieme, 378.
- Definition: BUSELMAIER, Werner (2012). Biologie für Mediziner. 12. neubearbeitete und erweiterte Aufl. Berlin, Heidelberg: Springer Verlag, 217.
- Context: BUSELMAIER, Werner (2012). Biologie für Mediziner. 12. neubearbeitete und erweiterte Aufl. Berlin, Heidelberg: Springer Verlag, 227.
- Images:
“Restriction Fragment Length Polimorphism”, National Center for Biotechnology Information: Probe: Reagents for Functional Genomics: http://www.ncbi.nlm.nih.gov/genome/probe/ doc/TechRFLP.shtml
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