- Institution/s: Universidad de Saarbrücken, Universidad de Valladolid
- Project: Diccionario Terminológico de Genética (Eurogene)
- Identification number: 128
- Subdomains: Studies of chromatin, Studies of DNA, Studies of RNA, Techniques
- Author/s: Ana María ALCONCHEL SEBASTIÁN, Augustine Edith EMENE, Inés PLAZA FONTANET, Rosario HERRERO
- Creation / modification date: 31-01-2014
- Term: telomere
- Gramatical category: s
- Definition: Complex structure at the end of a linear chromosome that performs several cellular functions.
- Context: When telomeres lose capping function, a DNA damage response is induced and the resultant telomere shortening is one of the factors that lead to an accumulation of unrepaired DNA damage during ageing, which causes cellular growth arrest.
- Expression: telomere shortening
- Weighting mark: nor
- Remission: abr, ADN. Source: Brachet T (2004) : Le professeur Jean Brachet, Mon Père, Edition l’Harmattan, Paris. P 4a.
- Sources:
- Term: SCANDALIOS, J.C.; WRIGHT,T.R.F. (eds.) (1992) Advances in Genetics, volume 30. San Diego: Academic Press, Inc.
- Definition: SCANDALIOS, J.C.; WRIGHT,T.R.F. (eds.) (1992) Advances in Genetics, volume 30. San Diego: Academic Press, Inc.
- Context: LENHARD RUDOLPH, K. (ed.) (2008) Telomeres and Telomerase in Ageing, Disease and cancer. Ulm: Springer
- Expression: LENHARD RUDOLPH, K. (ed.) (2008) Telomeres and Telomerase in Ageing, Disease and cancer. Ulm: Springer
- Images:
http://www.creces.cl/images/articulos/0902.13-1.jpg
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