Institution/s: Universidad de Valladolid, Universitatea de Vest din Timişoara
Project: Diccionario Terminológico de Genética (Eurogene)
Identification number: 144
Subdomains: Studies of chromatin, Studies of DNA, Studies of RNA, Techniques
Author/s: Bianca CONSTANTINESCU, Isaac MORENO RUIZ, María Eugenia HERRERAS , Marta VALDENEBRO ARENAS
Creation / modification date: 01-02-2014
Term: gene repression
Gramatical category: s
Definition: The inhibition of gene transcription of an operon; in prokaryotes the mechanism involves binding of the operon by a repressor, sometimes also requiring the binding of a corepressor or absence of an inducer. The end result is frequently a decrease in the level of an enzyme.
Context: The chosen strategy for finding tissue-specific gene repression was also applied to the liver as baseline instead of islets (5), and this resulted in the identification of liver-specifically repressed genes as the mirror situation of liver-specific genes.
Weighting mark: nor
Remission: abrform, SRY. Source: EMERY, A.E.H. y MUELLER, R.F. (1992) Elements of Medical Genetics, Churchill Livingstone: New York. 8th Edition (p. 95).