Institution/s: Universidad de Alicante, Universidad de Saarbrücken, Universidad de Valladolid, Universitatea de Vest din Timişoara
Project: Diccionario Terminológico de Genética (Eurogene)
Identification number: 74
Subdomains: Studies of chromatin, Studies of DNA, Studies of RNA, Techniques
Author/s: Andrea COCCARO CASTILLO, Bianca CONSTANTINESCU, Gloria GONZÁLEZ-CALERO, María Eugenia HERRERAS
Creation / modification date: 30-01-2014
Term: chromatid
Gramatical category: s
Definition: One of two identical halves of a replicated chromosome. During cell division, the chromosomes first replicate so that each daughter cell receives a complete set of chromosomes. Following DNA replication, the chromosome consists of two identical structures called sister chromatids, which are joined at the centromere.
Context: The spindle checkpoint detects improper kinetochore-microtubule attachments and translates these defects into biochemical activities that inhibit the anaphase-promoting complex or cyclosome (APC/C) throughout the cell to delay anaphase onset. A deficient spindle checkpoint leads to premature sister-chromatid separation and aneuploidy.
Weighting mark: nor
Remission: sin, anomalie génétique . Source: http://www.ac-nancy-metz.fr/enseign/svt/eleve/cyber/Vincent/anogenes.htm .
Sources:
Term: SEYFFERT, Wilhelm (Hrsg.) (2003). Lehrbuch der Genetik. Berlin: Spektrum Akademischer Verlag, 230.
Definition: TEUFEL, Andreas (2011). Humangenetik. Stuttgart: Urban & Fischer, 2.
Context: TEUFEL, Andreas (2011). Humangenetik. Stuttgart: Urban & Fischer, 13.