- Institution/s: Universidad de Alicante, Universidad de Valladolid
- Project: Diccionario Terminológico de Genética (Eurogene)
- Identification number: 187
- Subdomains: Studies of chromatin, Studies of DNA, Studies of RNA, Techniques
- Author/s: Andrea COCCARO CASTILLO, Augustine Edith EMENE, Carmen CUÉLLAR LÁZARO, Isaac MORENO RUIZ
- Creation / modification date: 01-02-2014
- Term: nucleic acid
- Gramatical category: s
- Definition: Any of a group of complex compounds found in all living cells and viruses, composed of purines, pyrimidines, carbohydrates, and phosphoric acid. Nucleic acids in the form of DNA and RNA control cellular function and heredity.
- Context: Introduction of use of nanoparticle based systems could improve the drug uptake and cytotoxity due to the coexistence of the chemosensitizer, anticancer drugs, and perhaps short nucleic acids such as MDR1siRNA in the same cell, but the precise mechanism of interaction warrants further investigation.
- Weighting mark: nor
- Sources:
- Term: EMERY, A. (2009), Elementos de genética médica. Barcelona: Ed. Elsevier, 13ª Edición. (Revisión científica a cargo del Dr. Rafael Oliva Virgili).
- Definition: http://www.edu.xunta.es/centros/iespuntacandieira/system/files/06_%25C3%2581cidos_nucleicos.pdf; http://campus.usal.es/~dbbm/modmol/modmol06/index06.html
- Context: Enciclopedia Salvat Universal (1998). Tomo XVIII. Barcelona: Salvat.
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