edugeneedugene2013
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  • Institution/s: Universidad de Valladolid, Université d'Artois
  • Project: Diccionario Terminológico de Genética (Eurogene)
  • Identification number: 38
  • Subdomains: Studies of chromatin, Studies of DNA, Studies of RNA, Techniques
  • Author/s: Carmen CUÉLLAR LÁZARO, Marie-Hélène GARCIA, Marta SERNA GIL, Regina CAVA GARCÍA
  • Creation / modification date: 02-03-2014
  • Term: intron
  • Gramatical category: s
  • Definition: Intervening sequences that are present in the genes of eukaryotes and are removed from the RNA transcript shortly after transcription.
  • Context: After discarding those questionable introns that do not contain correct splice sites, the final database contained 17 102 introns, 21 019 exons and 2903 independent or quasi-independent genes.
  • Expression: Intron sequence Intron and exon
  • Weighting mark: nor
  • Remission: diaf_var, Hermafroditismo Fuente: BAJO ARENAS, José Manuel (2009). Fundamentos de Ginecología. Madrid: Ed. Médica Panamericana.
  • Sources:
    • Term: EMERY, A.E.H. y MUELLER, R.F. (1992) Elements of Medical Genetics, Churchill Livingstone: New York. 8th Edition.
    • Definition: FRANCIS, C. (2002). "A Computational Study of Gene Structure and Splicing in Model Eukaryote Organisms". Recuperado el 25 de abril de 2013 de: http://www.clarkfrancis.com/thesis/
    • Context: MICHAEL, D. y L. MANYUAN (1999). Intron-exon structures of eukaryotic model organisms. Nucleic Acids Research, 27, 3219-3228. Recuperado el 25 de abril de 2013 de: http://nar.oxfordjournals.org/content/27/15/3219.short
    • Expression: COULIE, P. G., LEHMANN, F. R. E. D. E. I. R. I. C., LETHE, B., HERMAN, J., LURQUIN, C., ANDRAWISS, M. y T. BOON (1995). A mutated intron sequence codes for an antigenic peptide recognized by cytolytic T lymphocytes on a human melanoma. Proceedings of the National Academy of Sciences, 92, 7976-7980. Recuperado el 25 de abril de 2013 de: http://www.pnas.org/content/92/17/7976.short YEAKLEY, J. M., HEDJRAN, F. A. R. A. H., MORFIN, J. P., MERILLAT, N. I. C. O. L. A., ROSENFELD, M. G. y R. B. EMESON (1993). Control of calcitonin/calcitonin gene-related peptide pre-mRNA processing by constitutive intron and exon elements. Molecular and cellular biology, 13, 5999-6011. Recuperado el 25 de abril de 2013 de: http://mcb.asm.org/content/13/10/5999.short
  • Images:
    • intron
      SCHAAF, Christian, ZSCHOCKE, Johannes (2013). Basiswissen Humangenetik. 2. Aufl. Berlin, Heidelberg: Springer Verlag, 12.
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